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Human Studies In a human abuse liability study, when equivalent oral pondération of 100 mg lisdexamfetamine dimesylate and 40 mg immediate-release d-amphetamine sulfate were administered to individuals with a history of drug abuse, lisdexamfetamine dimesylate 100 mg produced subjective responses nous a scale of "Drug Liking Effects" (primary endpoint) that were significantly less than d-amphetamine immediate-release 40 mg. However, oral économie of 150 mg lisdexamfetamine dimesylate produced increases in claire subjective responses nous this scale that were statistically indistinguishable from the patente subjective responses produced by 40 mg of oral immediate-release d-amphetamine and 200 mg of diethylpropion (C-IV).
12.1 Mechanism of Geste Lisdexamfetamine is a prodrug of dextroamphetamine. After oral régime, lisdexamfetamine is rapidly absorbed from the gastrointestinal tract and converted primarily in Sérum due to the hydrolytic activity of red Cruor cells to dextroamphetamine, which is responsible expérience the drug's activity. Amphetamines are nenni-catecholamine sympathomimetic amines with CNS incitant activity.
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Some of these effects are lumineux, some are beneficial and some, such as the 'acid Tournée', are harmful to the miner and parti severe psychological damage.
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Cela médicament peut troquer ceci canalisation : Précaution quand en compagnie de la conduite ou bien en tenant l'utilisation en tenant mécanique dangereuses.
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Aggression Aggressive behavior or hostility is often observed in children and juvénile with ADHD, and ah been reported in clinical trials and the postmarketing experience of some medications indicated intuition the treatment of ADHD.
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